产品货号：
Z35020
中文名称：
LYN Purified抗体
英文名称：
Anti-LYN Purified Antibody (Clone#LYN-01)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LYN Purified Antibody (Clone#LYN-01) |
| 指标别名 | JTK8;LYN;Tyrosine protein kinase Lyn |
| 克隆性 | Monoclonal |
| 检验物种 | rat,human,mouse |
| 应用范围 | IP,WB,ICC |
| 基因名称 | LYN |
| 克隆号 | LYN-01 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Bacterially expressed recombinant fragment of human Lyn (aa 8 - 238).The antibody LYN-01 reacts with Lyn (p56/p53),a non-receptor Src-family tyrosine kinase expressed in hematopoietic tissues (intracellular antigen). |
| 计算分子量 | 59kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | Lyn is a Src-family protein tyrosine kinase that is predominantly expressed in hematopoietic cells.It is associated with a number of cell surface receptors including the B cell antigen receptor (BCR) and Fc receptors.Upon their triggering,Lyn phosphorylates subunits of these receptors in a cholesterol-dependent manner,utilizing the plasma membrane lipid raft system.The phosphorylated intracellular domains of the receptors are accessible for cytoplasmic Syk tyrosine kinase,which is activated by Lyn-mediated phosphorylation and which transduces the signal to downstream adaptors.Lyn is abnormally distributed in acute myeloid leukemia cells and seems to be a novel pharmacologic target of this disease. |
| Uniprot ID | P07948 |
| 基因名全称 | LYN proto-oncogene,Src family tyrosine kinase |
| 蛋白名全称 | Tyrosine-protein kinase Lyn |
| 推荐稀释比 | Western blotting:1～2μg/mL. |
相关搜索：LYN Purified抗体，LYN Purified单抗，Anti-LYN Purified Antibody (Clone#LYN-01)